Table 5Strengths and Limitations of Systematic Reviews Using AMSTAR 212

StrengthsLimitations
Meyer et al. (2022) 16
  • The research question and inclusion criteria were clearly defined
  • Review methods were established before review was conducted (PROSPERO: CRD42021228806)
  • Review authors did screen multiple databases and references of relevant review articles
  • Literature screening was conducted by 2 independent review authors
  • Search timeframe was not restricted
  • Review authors provided adequate detail of included studies
  • Risk of bias was assessed for all included studies using the RoB2 Cochrane Collaboration’s tool for assessing risk of bias in RCTs
  • Combination of results were assessed using pooled relative risk, risk difference and mean difference obtained using models with random effects
  • Heterogeneity was assessed using the Q-test and quantified using the I2 value, and heterogeneity was discussed
  • Publication bias was assessed using funnel plots
  • Review authors did not justify included study designs or exclusion criteria
  • Justification for publication restrictions were not provided (Non-RCTs study design, English only)
  • Unclear if data extraction was performed in duplicate
  • List of excluded studies and justification for exclusion was not provided
  • Review authors did not report on sources of funding for included studies
  • Potential impact of risk of bias for individual studies on the results on the meta-analysis was not assessed
  • Review authors did not report if they had any conflicts of interest or received any funding
Tang et al. (2022) 17
  • The research question and inclusion criteria were clearly defined and included PICO components
  • Review authors did screen multiple databases and reference of included and relevant studies
  • Literature screening was conducted by 2 independent review authors
  • No publication restrictions were included in the search
  • Data extraction was conducted by 2 independent review authors
  • Review authors provided adequate detail of included studies
  • Risk of bias was assessed for all included studies using the Cochrane Collaboration tool for RCTs and the Newcastle-Ottawa score for non-randomized studies
  • Combinations of results were assessed using relative risk and mean difference while considering heterogeneity within and between studies
  • Heterogeneity was assessed using the chi-square test and I2
  • Publication bias was assessed using funnel plots
  • The review authors reported receiving no funding or potential conflict of interest
  • Unclear if review protocol was registered in advance
  • Review authors did not justify included study designs or exclusion criteria
  • List of excluded studies was not provided
  • Review authors did not report on sources of funding for included studies
Chaudhry et al. (2021) 18
  • The research question and inclusion criteria were clearly defined
  • Review authors did screen multiple databases
  • Literature search screening was conducted by 2 independent review authors
  • Search timeframe was not restricted
  • Review authors provided adequate detail of included studies
  • Risk of bias was assessed using Cochrane RoB tools for RCTs
  • Review authors disclosed any potential conflicts of interest
  • Unclear if review protocol was registered in advance
  • Review authors did not justify included study designs or exclusion criteria
  • Justification for publication restrictions were not provided (non-RCT study designs, English studies only)
  • Unclear if authors searched references or any additional sources of information
  • Unclear if data extraction was performed in duplicate
  • List of excluded studies was not provided
  • Description of statistical analyses was not provided
  • Risk of bias was not accounted for in the interpretation of discussion of results
  • Publication bias was not assessed
  • Review authors did not report on funding sources of included studies
  • Review authors did not report if they received any funding
Elhenawy et al. (2021) 19
  • The research question and inclusion criteria were clearly defined
  • Review methods were established before review was conducted (PROSPERO: CRD42015016771)
  • Review authors did screen multiple databases and reference of included and relevant studies
  • No publication restrictions were included in the search
  • Literature search screening was conducted by 2 independent review authors
  • Data extraction was conducted by 2 independent review authors
  • Review authors provided adequate detail of included studies
  • Risk of bias was assessed using Cochrane RoB tools
  • Combinations of results were assessed using risk ratios and mean difference while considering heterogeneity within and between studies
  • The Cochrane’s Q-test was used to calculate the statistical heterogeneity among studies
  • Overall quality of evidence was determined using GRADE which included an assessment of publication bias
  • Potential impact of risk of bias for individual studies on the results on the meta-analysis was assessed
  • Review authors did disclose any potential conflicts of interest
  • Review authors did not justify included study designs or exclusion criteria
  • List of excluded studies was not provided
  • Review authors did not report funding sources of included studies
  • Review authors did not report if they received any funding
Jones et al. (2021) 20
  • The research question and inclusion criteria were clearly defined
  • Review methods were established before review was conducted
  • Review authors did screen multiple databases and reference of included and relevant studies
  • Literature search screening was conducted by 2 independent review authors
  • Search timeframe was not restricted
  • Review authors provided adequate detail of included studies
  • Risk of bias was assessed using Cochrane RoB tools
  • Overall quality of evidence was determined using GRADE which included an assessment of publication bias
  • Risk of bias was accounted for in the interpretation of discussion of results
  • The review authors reported funding source and potential conflict of interest
  • Review authors did not justify exclusion criteria
  • List of excluded studies was not provided
  • Unclear if data extraction was performed in duplicate
  • Unclear if additional restrictions were included in the literature search (e.g., language)
  • Description of statistical analyses was not provided
  • Review authors did not report funding sources of included studies
Moon et al. (2021) 21
  • The research question and inclusion criteria were clearly defined
  • Review methods were established before review was conducted (PROSPERO: 160868)
  • Review authors did screen multiple databases
  • Literature search screening was conducted in duplicate with multiple authors
  • Data extraction was performed by one author and checked by another author
  • Review authors provided adequate detail of included studies
  • Risk of bias was assessed for all included studies using the Cochrane Collaboration tool for RCTs and the Newcastle-Ottawa score for non-randomized studies
  • The review authors reported receiving no funding or potential conflict of interest
  • Review authors did not justify included study designs or exclusion criteria
  • Justification for publication restrictions were not provided (Potential time frame restrictions, English studies only)
  • Unclear if authors searched references or any additional sources of information
  • List of excluded studies was not provided
  • Unclear if publication bias was assessed
  • Description of statistical analyses was not provided
  • Risk of bias was not accounted for in the interpretation of discussion of results
  • Review authors did not report funding sources of included studies

AMSTAR 2 = A MeaSurement Tool to Assess systematic Reviews 2; GRADE = Grading of Recommendations Assessment, Development, and Evaluation; RCT = randomized controlled trial; RoB = risk of bias.

From: Intravenous Iron Preparations for Patients Undergoing Elective Surgery: A 2022 Update

Cover of Intravenous Iron Preparations for Patients Undergoing Elective Surgery: A 2022 Update
Intravenous Iron Preparations for Patients Undergoing Elective Surgery: A 2022 Update: Rapid Review [Internet].
Hill S, Severn M; Authors.
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