Probe Reports from the NIH Molecular Libraries Program [Internet].
Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table S1Activity of cherry-picked HTS hits against pPAFAH as assessed by gel-based competitive ABPP (AID 588474)
| Compound lab name | SID | CID | % Inhibition pPAFAH (5 μM Cpd) |
|---|---|---|---|
| A03 | 49818553 | 24817488 | 9% |
| A04 | 49825105 | 4869553 | 36% |
| A05 | 14723122 | 1075762 | 39% |
| A06 | 17413867 | 5734364 | 91% |
| A07 | 49672084 | 2729092 | 82% |
| A08 | 49717433 | 4095299 | 31% |
| A09 | 49646777 | 16406874 | 44% |
| A10 | 49647446 | 4868796 | 34% |
| A11 | 24803039 | 3713423 | −3% |
| A12 | 49716397 | 1506393 | 21% |
| B03 | 865529 | 666788 | 15% |
| B04 | 49647532 | 728803 | 24% |
| B05 | 49735046 | 4351780 | 30% |
| B06 | 7977938 | 1037259 | 40% |
| B07 | 24837627 | 4318214 | 44% |
| B08 | 49677790 | 1582142 | 93% |
| B09 | 24707853 | 5459455 | 84% |
| B10 | 24820189 | 1471280 | −3% |
| B11 | 24823024 | 16010039 | 6% |
| B12 | 4244777 | 3239329 | 14% |
| C03 | 49825219 | 8016642 | 28% |
| C04 | 56463309 | 186136 | 16% |
| C05 | 17414793 | 5337390 | 23% |
| C06 | 22405959 | 2435938 | 30% |
| C07 | 49827389 | 24819624 | 10% |
| C08 | 49717475 | 24789974 | 8% |
| C09 | 4241429 | 3236404 | 13% |
| C10 | 7965604 | 5142655 | 0% |
| C11 | 85198338 | 3557212 | 19% |
| C12 | 4241939 | 3236852 | 11% |
| D03 | 4265651 | 893857 | 23% |
| D04 | 4244235 | 3238857 | 22% |
| D05 | 14735286 | 2901168 | 35% |
| D06 | 14736542 | 1291961 | 43% |
| D07 | 24789783 | 1092909 | 20% |
| D08 | 4262614 | 675677 | 5% |
| D09 | 14727785 | 983012 | 28% |
| D10 | 14746123 | 2251357 | 22% |
| D11 | 49647657 | 8016217 | 26% |
| D12 | 85269573 | 3642677 | 20% |
| E03 | 14730879 | 2227768 | 26% |
| E04 | 49717482 | 4299457 | 18% |
| E05 | 4246105 | 3240490 | 24% |
| E06 | 49719647 | 16031740 | 13% |
| E07 | 3712811 | 847829 | 17% |
| E08 | 85271190 | 3666144 | 36% |
| E09 | 4244707 | 3239272 | 10% |
| E10 | 49825244 | 24818849 | 30% |
| E11 | 57263442 | 7613142 | 7% |
| E12 | 14741589 | 1835517 | 5% |
| F03 | 845873 | 648231 | 12% |
| F04 | 49733222 | 2176514 | 5% |
| F05 | 57257880 | 25162008 | 64% |
| F06 | 24790869 | 5049848 | 10% |
| F07 | 17385991 | 2104350 | 6% |
| F08 | 49820822 | 4868856 | 31% |
| F09 | 4258391 | 973780 | 18% |
| F10 | 49717429 | 24789969 | 18% |
| F11 | 24782606 | 16187915 | 24% |
| F12 | 17385869 | 11839061 | 0% |
| G03 | 26671454 | 2929094 | 15% |
| G04 | 24818607 | 1483231 | 40% |
| G05 | 22409568 | 3270837 | 24% |
| G06 | 49717013 | 7573833 | 18% |
| G07 | 49645759 | 24747337 | 100% |
| G08 | 56323414 | 9314931 | 44% |
| G09 | 57257322 | 25161540 | −9% |
| G10 | 49736277 | 24793740 | 21% |
| G11 | 57265894 | 16307002 | 75% |
| G12 | 14739000 | 2238485 | 8% |
| H03 | 17504315 | 12004490 | 45% |
| H04 | 7967489 | 651937 | 55% |
| H05 | 846032 | 648404 | 65% |
| H06 | 46500928 | 3241208 | 10% |
| H07 | 24791358 | 3271558 | 40% |
| H08 | 7972767 | 807071 | 55% |
| H09 | 56422452 | 28693 | 15% |
| H10 | 4251449 | 3245135 | 8% |
| H11 | 49822987 | 16406937 | 11% |
| H12 | 56324777 | 24983114 | 7% |
| I03 | 57258588 | 25162597 | 41% |
| I04 | 853294 | 655946 | 84% |
| I05 | 4265310 | 977306 | 44% |
| I06 | 49648667 | 16457475 | 23% |
| I07 | 56315773 | 16231989 | 84% |
| I08 | 49732024 | 6462016 | 22% |
| I09 | 17516379 | 5122563 | 56% |
| I10 | 49728290 | 1092926 | 3% |
| I11 | 49728289 | 1092856 | 21% |
| I12 | 4256580 | 1092921 | 7% |
| J03 | 22409711 | 15945323 | 23% |
| J04 | 3714380 | 2998774 | 38% |
| J05 | 49815912 | 24543718 | 55% |
| J06 | 56321507 | 24981655 | 28% |
| J07 | 17432567 | 1345082 | 45% |
| J08 | 56317169 | 24979689 | 16% |
| J09 | 7966421 | 5308219 | 53% |
| J10 | 56324883 | 24983159 | 42% |
| J11 | 26727296 | 2726311 | 99% |
| K03 | 85269967 | 2327104 | 21% |
| K04 | 17431795 | 2282503 | 48% |
| K05 | 14725991 | 1160042 | 43% |
| K06 | 85270454 | 4783698 | 17% |
| K07 | 49819107 | 2213570 | 12% |
| K08 | 49728592 | 1092738 | 69% |
| K09 | 14723216 | 1092878 | 38% |
| K10 | 49672846 | 4876778 | 35% |
| K11 | 17506881 | 2971862 | 8% |
| L03 | 26664791 | 288774 | 29% |
| L04 | 3716333 | 2084085 | 54% |
| L05 | 26669611 | 2972134 | 47% |
| L06 | 56324509 | 24982966 | 24% |
| L07 | 14739800 | 1333712 | 27% |
| L08 | 17508962 | 1150498 | 39% |
| L09 | 4241284 | 1480154 | 8% |
| L10 | 49829001 | 16406654 | 40% |
| L11 | 49732864 | 20968792 | 5% |
| M03 | 14733155 | 4048822 | 52% |
| M04 | 24831877 | 4374113 | 48% |
| M05 | 49823145 | 4869036 | 53% |
| M06 | 49829271 | 4869139 | 19% |
| M07 | 24823472 | 16195494 | 3% |
| M08 | 49726570 | 3152114 | 17% |
| M09 | 26729061 | 2795735 | 12% |
| M10 | 17414795 | 5337401 | 9% |
| M11 | 49665098 | 4869534 | 18% |
| N03 | 14728016 | 847926 | 41% |
| N04 | 14742766 | 1951620 | 70% |
| N05 | 49828442 | 16406741 | 53% |
| N06 | 56315412 | 18108581 | 18% |
| N07 | 14733456 | 3505699 | 18% |
| N08 | 57260648 | 16306230 | 78% |
| N09 | 14731640 | 1298699 | 57% |
| N10 | 49717138 | 16034280 | 4% |
| N11 | 56322366 | 24982068 | 20% |
| O03 | 24819918 | 1486626 | 36% |
| O04 | 7977385 | 749766 | 22% |
| O05 | 49828888 | 17584900 | 73% |
| O06 | 49829242 | 4967664 | 37% |
| O07 | 49820844 | 24818165 | 10% |
| O08 | 49645631 | 24747236 | 29% |
| O09 | 49733753 | 1091834 | 24% |
| O10 | 14739190 | 955142 | 9% |
| O11 | 49645884 | 16406847 | 21% |
| P03 | 4264232 | 2236013 | 79% |
| P04 | 49717421 | 4103720 | 41% |
| P05 | 57263037 | 4592650 | 53% |
| P06 | 17413874 | 2229425 | 46% |
| P07 | 87334149 | 16060009 | 18% |
| P08 | 14723147 | 1008028 | 30% |
| P09 | 4257433 | 1378785 | 98% |
| P10 | 14725052 | 1015202 | 46% |
| P11 | 14737509 | 4048820 | 29% |