CID/ML#Target NameEC50 (nM) [SID, AID]Anti-target Name(s)IC50/EC50 (μM) [SID, AID]Fold SelectiveSecondary Assay(s) Name: IC50/EC50 (nM) [SID, AID]
CID 45115620/ML218Cav3.2 (Ca2+flux)150, [SID 92310249, AID 449739, AID 489005, AID 493021, AID 493022, AID 493023, AID 493041, AID 504619]L/N-Type Ca2+

hERG

Na+/K+ current in rat DRG		>10, [SID 92310249, AID 504584]

>10 [SID 92310249, AID 504584]

>10 [SID 92310249, AID 504579]		>60

>60

>60		Cav3.2_IWS: 310 [SID 92310249, AID 504425]

Cav3.3_IWS: 270 [SID 92310249, AID 504425]

From: Scaffold Hopping Affords a Highly Selective in vitro and in vivo T-Type Calcium Inhibitor Probe Free From IP Issues

Cover of Probe Reports from the NIH Molecular Libraries Program
Probe Reports from the NIH Molecular Libraries Program [Internet].
Copyright Notice

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.