Table 4.

Treatment of Manifestations in Individuals with Costeff Syndrome

Manifestation/ConcernTreatmentConsiderations/Other
Visual impairment Standard treatment(s) as recommended by ophthalmologist
  • Eval for visual aids
  • Community vision services through early intervention or school district
Spasticity Orthopedics / physical medicine & rehab / PT&OT incl stretching to help avoid contractures & fallsConsider need for positioning & mobility devices, disability parking placard.
Poor weight gain /
Failure to thrive 		Feeding therapyLow threshold for clinical feeding eval &/or radiographic swallowing study if clinical signs or symptoms of dysphagia
DD See DD/ID Management Issues.
Family/Community
  • Ensure appropriate social work involvement to connect families w/local resources, respite, & support.
  • Coordination of care to manage multiple subspecialty appointments, equipment, medications, & supplies
  • Ongoing assessment of need for palliative care involvement &/or home nursing
  • Consider involvement in adaptive sports or Special Olympics.

DD = developmental delay; ID = intellectual disability; OT = occupational therapy; PT = physical therapy

From: Costeff Syndrome

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