Table 1List of all assays screened

PubChem AIDTypeTargetConc. RangeSamples Tested
2242Primary qHTSacid alpha-glucosidase57.5 μM – 0.7 nM199,303
2112Primary qHTSacid alpha-glucosidase57.5 μM – 0.7 nM236,748
2100Primary qHTSacid alpha-glucosidase57.5 μM – 0.7 nM304,253
2101Counterscreenbeta-glucosidase57.5 μM – 0.7 nM326,770
1467Counterscreenalpha-galactosidase57.5 μM – 0.7 nM229,459
2107Counterscreenalpha-galactosidase57.5 μM – 0.7 nM239,498
2115Confirmatoryacid alpha-glucosidase287 μM – .001μM296
2113Confirmatoryacid alpha-glucosidase287 μM – 0.001 μM296
2110Secondaryacid alpha-glucosidase282 μM – 0.001 μM70
2111Secondaryacid alpha-glucosidase282 μM – 0.001 μM59
2108Counterscreenalpha-galactosidase287 μM – 0.001 μM296
2109Counterscreenalpha-galactosidase287 μM – 0.001 μM296
2293Secondaryacid alpha-glucosidase10 μM – 0.1 μM1
602122Secondaryacid alpha-glucosidase15 μM2
1473Summaryacid alpha-glucosidaseN/AN/A

From: Discovery, SAR, and Biological Evaluation of a Non-Inhibitory Chaperone for Acid Alpha Glucosidase

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