Table 5.

Autosomal Dominant Epilepsy with Auditory Features: Treatment of Manifestations

Manifestation/ConcernTreatmentConsiderations/Other
Epilepsy Standardized treatment w/ASM by epileptologist or experienced neurologist
  • Most persons are responsive to standard ASMs & in most cases monotherapy is effective for complete seizure control. 1
  • Education of parents/caregivers 2
Psychiatric issues Standardized treatment by psychiatrist
Family/Community Ensure appropriate social work involvement to connect families w/local resources& support.Ongoing assessment of need for support

ASM = anti-seizure medication

1.

Traditionally sodium channel blockers such as carbamazepine have been more frequently used with clear benefit. However, no clinical trials of different anti-seizure medications have been carried out, therefore definite therapeutic guidelines have not been published to date. Total remission might be lower than expected and treatment withdrawal might lead to relapses in some individuals.

2.

Education of parents/caregivers regarding common seizure presentations is appropriate. For information on non-medical interventions and coping strategies for children diagnosed with epilepsy, see Epilepsy Foundation Toolbox.

From: Autosomal Dominant Epilepsy with Auditory Features

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