Table 8.

Focused Physical Examination in a Patient with Osteoporosis

Component of physical examExample of finding of potential skeletal importancePotential clinical implications for skeletal health
Vital signsLow body weight or body mass indexAnorexia nervosa
Loss of heightVertebral fracture
Loss of weightMalignancy, malabsorption
SkinUrticaria pigmentosa
Dermatitis herpetiformis
Systemic mastocytosis
Celiac disease
Striae, acneCushing’s syndrome, exogenous glucocorticoids
HeadCranial dysostosisHypophosphatasia
EyesBlue scleraOsteogenesis imperfect
EarsHearing lossOsteogenesis imperfecta, sclerosteosis
NoseAnosmiaKallmann syndrome
ThroatPoor dentitionIncreased risk of osteonecrosis of the jaw
NeckThyromegalyThyrotoxicosis
LungsDecreased breath soundsChronic obstructive pulmonary disease
HeartAortic insufficiencyMarfan’s syndrome
MusculoskeletalKyphosisVertebral fractures
Spinous process tendernessAcute vertebral fracture
Decreased space between lower ribs and pelvisVertebral fractures
Tender bonesOsteomalacia
Inflammatory joint diseaseRheumatoid arthritis
Hypermobility of jointsEhlers-Danlos syndrome
Muscle weaknessVitamin D deficiency, osteomalacia
AbdomenHepatomegalyChronic liver disease
Surgical scarsBariatric surgery, gastrectomy
GenitaliaTesticular atrophyHypogonadism
NeurologicalPoor balanceHigh fall risk, vitamin D deficiency
DementiaPoor adherence to therapy, high fall risk

This table provides examples of findings on physical exam that may be helpful in the evaluation of skeletal health. It is not intended to show all findings of importance.

From: Osteoporosis: Clinical Evaluation

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