Table 33.

Advantages and Disadvantages of Colesevelam

AdvantagesDisadvantages
Lowers LDL cholesterolIncreases triglyceride levels particularly if already high
Minimal systemic effectsGI side effects
Once a day administration possibleInhibits the absorption of other drugs
No hypoglycemiaModest effect on A1c
Weight neutralRelatively Expensive

From: Oral and Injectable (Non-Insulin) Pharmacological Agents for the Treatment of Type 2 Diabetes

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