Table 10. [Recommended Surveillance for Individuals with Hereditary Fructose Intolerance]. - GeneReviews®

System/Concern	Evaluation	Frequency
Diet/Nutrition	Dietary assessment by nutritionist as child grows, develops different tastes, & tries different foods Monitor for vitamin & mineral deficiencies.	Every 3-4 mos in 1st yr of life; every 6-12 mos thereafter
Liver dysfunction/ NAFLD	Abdominal ultrasound, liver function tests to assess progression of NAFLD	Every 6-12 mos
Renal dysfunction	BUN, creatinine, cystatin C, urine amino acids, plasma electrolytes to assess renal function (in setting of unintentional, ongoing ingestion of fructose)	Every 6-12 mos
Hypoglycemia	Plasma glucose	As needed for findings such as lethargy, seizures, jitteriness, diaphoresis
Chronic excess fructose ingestion	N-glycan eval Plasma lysosomal enzyme analysis Dietary intake assessment	Every 6-12 mos

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