Table 5.

Recommended Surveillance for Individuals with ADNP-Related Disorder

Manifestation/ConcernTreatmentFrequency
Feeding
  • Measurement of growth parameters
  • Eval of nutritional status & safety of oral intake
At each visit
Musculoskeletal Physical medicine, OT/PT assessment of mobility, self-help skills
Neurologic
  • Monitor those w/seizures as clinically indicated.
  • Assess for new manifestations (e.g., seizures, changes in tone, movement disorders).
Development Monitor developmental progress & educational needs.
Psychiatric/Behavioral Behavioral assessment for anxiety, attention, & aggressive or self-injurious behavior
Eyes Visual assessmentAnnually
Gastrointestinal Monitor for constipation & signs/symptoms of gastrointestinal reflux.At each visit
Family/Community Assess family need for social work support (e.g., palliative/respite care, home nursing, other local resources) & care coordination.

OT = occupational therapy; PT = physical therapy

From: ADNP-Related Disorder

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