Appendix Table CSystem-Level Interventions That Improve or Reduce Antibiotic Prescribing for Acute RTIs*

CategoryAbsolute ChangeResultsNumber of StudiesSOE
Electronic decision support vs. usual care
 Overall prescribing (systems with ≥50% use)-5% to -9%Greater reduction with decision support: RR 0.73 (95% CI, 0.58 to 0.92)2 RCTs Image clinantibiofu1.jpg
 Inappropriate prescribing (for acute bronchitis and AOM)-3% to -24%Greater reduction with decision support2 RCTs Image clinantibiofu1.jpg
 Adverse consequences—No difference in health care utilization or complications1 RCT Image clinantibiofu2.jpg
*

All populations are adults and children with acute RTIs.

AOM = acute otitis media; CI = confidence interval; RCT = randomized controlled trial; RR = relative risk; RTI = respiratory tract infection; SOE = strength of evidence

From: Interventions To Improve Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections

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