Table I-15Exposure-based therapy compared with relaxation

Domains Pertaining to Strength of EvidenceMagnitude of EffectStrength of Evidence
Number of Studies;
Number of Subjects		Risk of Bias; DesignConsistencyDirectnessPrecisionSummary Effect Size (95% CI)High, Moderate, Low, Insufficient
PTSD Symptom Reduction: CAPS
3; 155Medium; RCTsConsistentDirectImpreciseSMD -0.45 (-0.78 to -0.13), 3 trials, N=155Moderate
Loss of Diagnosis
2; 85Medium; RCTsConsistentDirectImpreciseRD range 0,20 to 0.47, both trials favored CBT-exposure, p<0.05 in 2 of 2 trialsModerate
Prevention/reduction of comorbid depression: BDI or HAM-D
3; 155Medium; RCTsConsistentDirectImpreciseSMD -0.39 (-0.71 to -0.07), 3 trials, N=155;Moderate

NA = not applicable

From: Appendix I, Strength of Evidence

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.
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