| Domains Pertaining to Strength of Evidence | Magnitude of Effect | Strength of Evidence | ||||
|---|---|---|---|---|---|---|
| Number of Studies; Number of Subjects | Risk of Bias; Design | Consistency | Directness | Precision | Summary Effect Size (95% CI) | High, Moderate, Low, Insufficient |
| PTSD Symptom Reduction: CAPS | ||||||
| 3; 199 | 2 Medium, 1 Low; RCTs | Consistent | Direct | Imprecise | P=ns in 3 of 3 trials | Low for no difference |
| Symptom Remission | ||||||
| 0; 0 | NA | NA | NA | NA | NA | Insufficient |
| Loss of Diagnosis | ||||||
| 3; 199 | 2 Medium, 1 Low; RCTs | Inconsistent | Direct | Imprecise | No significant difference between groups, 2 of 3 favored PE and 1 of 3 favored EMDR | Insufficient |
| Prevention/reduction of comorbid depression: BDI | ||||||
| 2; 91 | Medium; RCTs | Consistent | Direct | Imprecise | P=ns | Insufficient |
CI = confidence interval; NA = not applicable; PE = prolonged exposure; RCT = randomized controlled trial
From: Appendix I, Strength of Evidence
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