Table I-17Exposure-based therapy compared with IPT

Domains Pertaining to Strength of EvidenceMagnitude of EffectStrength of Evidence
Number of Studies;
Number of Subjects
Risk of Bias; DesignConsistencyDirectnessPrecisionSummary Effect Size (95% CI)High, Moderate, Low, Insufficient
PTSD Symptom Reduction: CAPS
1; 78Medium; RCTNA, single studyDirectImprecisep=nsInsufficient
Symptom Remission
1;78NANA, single studyNANARD 0.03, p=nsInsufficient
Prevention/reduction of comorbid depression: HAM-D
1;78Medium; RCTNA, single studyDirectImprecisep=nsInsufficient
Quality of Life
1; 78Medium, RCTNA, single studyDirectImpreciseNo significant difference between PE and IPT (−17.9 vs. −11.3, p=0.061)Insufficient

CI = confidence interval; NA = not applicable; PE = prolonged exposure; RCT = randomized controlled trial

From: Appendix I, Strength of Evidence

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.

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