| Domains Pertaining to Strength of Evidence | Magnitude of Effect | Strength of Evidence | ||||
|---|---|---|---|---|---|---|
| Number of Studies; Number of Subjects | Risk of Bias; Design | Consistency | Directness | Precision | Summary Effect Size (95% CI) | High, Moderate, Low, Insufficient |
| PTSD Symptom Reduction: CAPS or PSS-I | ||||||
| 4; 299 | Medium; RCTs | Inconsistent | Direct | Imprecise | Two studies favored exposure + CR, one study favored CR; p=ns for 4 of 4 trials | Insufficient |
| Loss of Diagnosis | ||||||
| 3; 146 | Medium; RCTs | Imprecise | Direct | Imprecise | P=ns for 3 of 3 studies, one favored PE and two favored PE+CR | Insufficient |
| Prevention/reduction of comorbid depression: BDI | ||||||
| 4; 299 | Medium; RCTs | Consistent | Direct | Imprecise | P=ns in 4 of 4 studies | Low for no benefit |
CI = confidence interval; NA = not applicable; RCT = randomized controlled trial
From: Appendix I, Strength of Evidence
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