Table I-20, CBT-mixed interventions compared with relaxation: Head-to-head trials - Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update

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	Domains Pertaining to Strength of Evidence				Magnitude of Effect	Strength of Evidence
Number of Studies; Number of Subjects	Risk of Bias; Design	Consistency	Directness	Precision	Summary Effect Size (95% CI)	High, Moderate, Low, Insufficient
PTSD Symptom Reduction by CAPS
2; 85	Medium; RCTs	Consistent	Direct	Imprecise	WMD range −24.0 to −21.2, p<0.05 in 2 of 2 trials	Low
Disability/functional impairment by GHQ Global Improvement
1; 45	Medium; RCT	NA, single study	Direct	Imprecise	RD 0.15, p=NS	Insufficient

: CI = confidence interval; NA = not applicable; RCT = randomized controlled trial

Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].

Comparative Effectiveness Review, No. 207.

Forman-Hoffman V, Middleton JC, Feltner C, et al.

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