| Domains Pertaining to Strength of Evidence | Magnitude of Effect | Strength of Evidence | ||||
|---|---|---|---|---|---|---|
| Number of Studies; Number of Subjects | Risk of Bias; Design | Consistency | Directness | Precision | Summary Effect Size (95% CI) | High, Moderate, Low, Insufficient |
| PTSD Symptom Reduction: CAPS | ||||||
| 2; 173 | Medium; RCT | Consistent | Direct | Imprecise | Between-group mean difference of -17.4 and -2.7 in individual studies Both favored treatment (1 of 2 studies p<0.05) | low |
| Symptom Remission | ||||||
| 2; 173 | Medium; RCT | Inconsistent | Direct | Imprecise | RD range −0.11 to 0.21, effect sizes in opposite directions | Insufficient |
| Loss of Diagnosis | ||||||
| 2; 173 | Medium; RCT | Inconsistent | Direct | Imprecise | RD range 0.01 to 0.26 | Insufficient |
| Prevention/reduction of comorbid depression: BDI | ||||||
| 1; 93 | Medium; RCT | NA, single study | Direct | Imprecise | WMD −4.1, p<0.05 | Insufficient |
| Prevention/reduction of comorbid anxiety | ||||||
| 1; 93 | Medium; RCT | NA, single study | Direct | Imprecise | p=ns | Insufficient |
BDI= Beck Depression Inventory; CI = confidence interval; mths, months; NA = not applicable; PTSD = post-traumatic stress disorder; RCT = randomized controlled trial
From: Appendix I, Strength of Evidence
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