Table A-2Pharmacological agents used in treating PTSD

ClassDrug
SSRIsCitalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline
SNRIsDesvenlafaxine, venlafaxine, and duloxetine
TCAsImipramine, amitriptyline, and desipramine
Other second-generation antidepressantsBupropion, mirtazapine, nefazodone, and trazodone
Alpha blockersPrazosin
Second-generation (atypical) antipsychoticsOlanzapine, risperidone, ziprasidone, aripiprazole and quetiapine
Anticonvulsants (mood stabilizers)Topiramate, tiagabine, lamotrigine, carbamazepine, and divalproex
BenzodiazepinesAlprazolam, diazepam, lorazepam, and clonazepam
Other medicationsNaltrexone, cycloserine, and inositol

PTSD = posttraumatic stress disorder; SNRI = serotonin and norepinephrine reuptake inhibitors; SSRI = selective serotonin reuptake inhibitor; TCA = tricyclic antidepressant.

From: Appendix A, Intervention Descriptions

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.

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