Table 13Results at the end of treatment for disability or functional impairment outcomes for CBT-mixed interventions compared with inactive controls

StudyArm (N)Outcome Measure(s)Baseline ValueEnd of Treatment ValueChange From BaselineP-ValueEffect Size (Cohen’s d)
Blanchard et al., 200336CBT-M (27)
WL (24)
GAFCBT-M: 53.9
WL: 56.0
75.8
60.4
NR<0.05NR
Bohus et al., 201323CBT-M (43)
UC-WL (39)
GAFCBT-M: 41.50
WL: 42.79
CBT-M: 49.44
WL: 43.79
NR<0.01NR
Cloitre, 200237CBT-M (31)
WL (27)
IIP

SAS-SR

ISEL
CBT-M: 1.88
WL: 1.70
CBT-M: 2.44
WL: 2.57
CBT-M: 24
WL: 23
CBT-M: 1.06
WL: 1.60
CBT-M: 2.06
WL: 2.47
CBT-M: 30
WL: 23
NR0.01

0.02

0.01
NR
Cottraux et al., 200831CBT-M (31)
SC (29)
Global Phobic Disability Subscale of FQNR4.4
4.0
−2.14
−2.0
0.86NR
Hollifield et al., 200732Acupuncture (29) (intervention not eligible)
CBT-M (28)
WL (27)
SDICBT-M: 4.09
WL: 4.0
3.3
3.96
NR<0.050.76
0.04
Spence et al., 201130CBT-M (23)
WL (21)
SDSCBT-M: 18.17
WL: 19.42
13.22
18.11
NR0.070.62

Note: Results are only presented for the relevant arms for this section (CBT-M and inactive comparators); values entered are means unless otherwise specified; p-values are for the comparison between CBT-M and inactive comparators.

CBT-M = cognitive behavioral therapy mixed; FQ = Fear Questionnaire (a self-rating inventory for evaluation of agoraphobia, social phobia, blood-injury phobia, anxiety-depression, and global phobic disability); GAF = Global Assessment of Functioning; IIP = Inventory of Interpersonal Problems; ISEL = Interpersonal Support Evaluation List; N = number; NR = not reported; SAS-SR = Social Adjustment Scale-Self Report; SC = supportive counseling; SDI = Sheehan Disability Inventory; SDS = Sheehan Disability Scale; UC = usual care; WL = wait-list.

From: Results

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.

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