Table 26Characteristics of included pharmacological trials that compared efficacy or comparative effectiveness between subgroups defined by patient characteristics or trauma types

StudyArm (N)Duration (Followup)Population Trauma TypeBaseline PTSD SeverityaMean Age (Y)% Female% Non-whiteRisk of Bias
van der Kolk et al., 200747EMDR (29)
Fluoxetine (30)
Placebo (29)
8 weeks (6 months)Male and female
Mixed subgroup analysis: child-onset and adult-onset trauma
71.2368333Medium
a

Data reported are mean CAPS total or range of mean CAPS total scores across groups unless otherwise specified.

CAPS = Clinician-Administered PTSD Scale; EMDR = eye movement desensitization and reprocessing; N = total number randomized/assigned to intervention and control groups; PTSD = posttraumatic stress disorder; y = year.

From: Results

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.

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