Table 27Characteristics of included studies directly comparing psychotherapy with pharmacotherapy

StudyArm (N)Duration (Followup)Population Trauma TypeBaseline PTSD SeverityaMean Age (Y)% Female% Non-whiteRisk of Bias
van der Kolk, 200747Fluoxetine (30)b
EMDR (29)
Placebo (29)
8 weeks (6 months)Male and female
Mixed
71368333Medium
a

Data reported are mean CAPS total score (1 week). The mean CAPS total score (1 month) was 74.0.

b

Titrated from 10 mg/day to max 60 mg/day (mean = 30 mg/day, mode = 40 mg/day).

CAPS = Clinician-Administered Post Traumatic Stress Disorder Scale; EMDR = eye movement desensitization and reprocessing; N = total number randomized/assigned to intervention and control groups; PTSD = posttraumatic stress disorder; y = year.

From: Results

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.

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