Table APsychological and pharmacological interventions used for treatment of patients with PTSD

Psychological InterventionsPharmacological Interventions
Cognitive behavioral therapy
  • Cognitive processing therapy
  • Cognitive restructuring
  • Exposure-based therapies
  • Coping skills therapy
  • Various “mixed” therapies

Eye movement desensitization and reprocessing

Other psychological or behavioral therapies
  • Psychodynamic therapy
  • Interpersonal therapy
  • Hypnosis/hypnotherapy
  • Mindfulness-based stress reduction
  • Eclectic psychotherapy
  • Brainwave neurofeedback

Energy psychology		Selective serotonin reuptake inhibitors:
  • Citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline

Selective serotonin and norepinephrine reuptake inhibitors:
  • Desvenlafaxine, venlafaxine, and duloxetine

Tricyclic antidepressants:
  • Imipramine, amitriptyline, and desipramine

Other second-generation antidepressants:
  • Bupropion, mirtazapine, nefazodone, and trazodone

Alpha blockers:
  • Prazosin

Second-generation (atypical) antipsychotics:
  • Olanzapine, risperidone, ziprasidone, aripiprazole and quetiapine

Anticonvulsants (mood stabilizers):
  • Topiramate, tiagabine, lamotrigine, carbamazepine, and divalproex

Benzodiazepines:
  • Alprazolam, diazepam, lorazepam, and clonazepam

Other medications:
Naltrexone, cycloserine, and inositol

PTSD = posttraumatic stress disorder. Bold: newly included treatment type examined in this updated review.

From: Evidence Summary

Cover of Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update
Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 207.
Forman-Hoffman V, Middleton JC, Feltner C, et al.
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