Table 4.

Treatment of Manifestations in Individuals with CM-AVM Syndrome

Manifestation/ConcernTreatmentConsiderations/Other
CMs & telangiectases Referral to dermatologistTo evaluate CMs of cosmetic concern & discuss risks & benefits of intervention
AVMs/AVFs Multidisciplinary team incl specialists in interventional radiology, neurosurgery, surgery, cardiology, & dermatology depending on location & symptoms
  • To determine treatment (e.g., embolization vs surgery)
  • Risks & benefits of intervention for AVMs & AVFs must be considered.
Cardiac overload Referral to cardiologist
Hemihyperplasia &/or leg length discrepancy Referral to orthopedistConsider:
  • Lymphangiography to evaluate for lymphatic malformations;
  • Compression stockings for those w/evidence of lymphedema.
Epistaxis (nosebleeds) Humidification & nasal lubricants; referral to otolaryngologistIf epistaxis, perform complete blood count for eval of anemia.

From: Capillary Malformation-Arteriovenous Malformation Syndrome

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