| Adverse Event* | PFMT + Trospium | PFMT + Pessaries + Vaginal Estrogen | TENS + PFMT + Vaginal Estrogen | TENS + Vaginal Estrogen |
|---|---|---|---|---|
| D/C due to AE | 3.2 [N = 31 (1 study)] | 0.9 [N = 1941 (1 study)] | ||
| Dry mouth | 22.6 [N = 31 (1 study)] | 1 [N = 1941 (1 study)] | ||
| Visual AE | 3.2 [N = 31 (1 study)] | |||
| AE (undefined/nonmajor) | 3.1 [N = 1941] (1 study)] | 0 [N = 137 (1 study)] | 0 [N = 105] (1 study)] | |
| AE, serious | 0.1 [N = 1941 (1 study)] | |||
| AE, treatment related | 2.2 [N = 1941 (1 study)] | |||
| CNS - dizziness | 0.2 [N = 1941 (1 study)] | |||
| Fatigue/drowsiness | 0.1 [N = 1941 (1 study)] | |||
| Gastrointestinal/abdominal symptoms (Constipation) | 0.4 [N = 1941 (1 study)] | |||
| Gastrointestinal/abdominal symptoms (Diarrhea) | 0.2 [N = 1941 (1 study)] | |||
| Gastrointestinal/abdominal symptoms (Nausea) | 0.5 [N = 1941 (1 study)] | |||
| Gastrointestinal/abdominal symptoms (Vomiting) | 0.4 [N = 1941 (1 study)] | |||
| Headache | 0.3 [N = 1941 (1 study)] | |||
| Pain - pelvic | 3.9 [N = 103 (1 study)] | |||
| Sleep disorder | 0.1 [N = 1941 (1 study)] | |||
| Sweating, excessive | 0.1 [N = 1941 (1 study)] |
The median and range are based on study arms. 1 arm = actual, 2 arms = range, 3+ arms median (range). If 1 or 2 studies have 3 or more arms, a median and range is given. Empty cells indicate that the outcome was not evaluated among the interventions designated in the given column
Abbreviations: AE = adverse event, D/C = discontinued, UTI = urinary tract infection, N = number, CNS = central nervous system, TENS = transcutaneous electrical nerve stimulation, PFMT = pelvic floor muscle training
Results in first line of each cell are given as percent adverse events, median (min, max). The numbers in brackets represent [total number of participants (number of studies)].
From: Results
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