Table 1.

The FDA (2017) Deutetrabenazine Dosage and Administration.

Disorder
Maximum dose of deutetrabenazine

Standard recommendation

Recommendation for CYP2D6 poor metabolizers

Chorea association with Huntington disease

48 mg
(24 mg twice daily)

36 mg per day
(18 mg twice daily)

Tardive dyskinesia

48 mg
(24 mg twice daily)

36 mg per day
(18 mg twice daily)

Please see Therapeutic Recommendations based on Genotype for more information from the FDA.
This FDA table is adapted from (1).

From: Deutetrabenazine Therapy and CYP2D6 Genotype

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