Table 3. [Biomarkers Available for use in...]. - Endotext

Test	Parameters included	number	PPV	NPV	Patients unable to be classified “grey zone”
NAFLD fibrosis score	Age, BMI, diabetes, AST/ALT ratio, platelets, albumin	733	82%	88%	24%
Fibrotest	Age, sex, total bilirubin, GGT, a2-macroglobulin, apolipoprotein A1, haptoglobin	267	60%	98%	32%
†FIB-4 index	Age, AST and ALT, platelets	541	80%	90%	30%
†BARD score	BMI, diabetes, AST/ALT ratio	827	43%	96%	N/A
NAFIC score	Ferritin, type IV collagen, insulin	619	36%	99%	15%
†Hepascore	Age, sex, total bilirubin, GGT, a2-macroglobulin, hyaluronic acid	242	57%	92%	11%

Test

Parameters included

number

PPV

NPV

Patients unable to be classified “grey zone”

NAFLD fibrosis score

Age, BMI, diabetes, AST/ALT ratio, platelets, albumin

733

82%

88%

24%

Fibrotest

Age, sex, total bilirubin, GGT,
a2-macroglobulin, apolipoprotein A1, haptoglobin

267

60%

98%

32%

†FIB-4 index

Age, AST and ALT, platelets

541

80%

90%

30%

†BARD score

BMI, diabetes, AST/ALT ratio

827

43%

96%

N/A

NAFIC score

Ferritin, type IV collagen, insulin

619

36%

99%

15%

†Hepascore

Age, sex, total bilirubin, GGT,
a2-macroglobulin, hyaluronic acid

242

57%

92%

11%

From: Nonalcoholic Fatty Liver Disease: The Overlooked Complication of Type 2 Diabetes

Endotext [Internet].

Feingold KR, Anawalt B, Blackman MR, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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