KEY POINTS
  • PrEP can be discontinued for individuals no longer at risk of HIV acquisition because they have eliminated the sex or drug use behaviors that put them at risk.
  • If renal dysfunction develops while an individual is taking TDF/FTC or TAF/FTC for PrEP, address potentially reversible causes before discontinuing oral PrEP.
  • CAB LA is an option for individuals with severe or end-stage renal impairment.
  • For an individual at ongoing risk because of nonadherence to protocols, make attempts to engage the patient in ongoing care and accommodate individual needs before discontinuing PrEP.

From: PrEP to Prevent HIV and Promote Sexual Health

Cover of PrEP to Prevent HIV and Promote Sexual Health
PrEP to Prevent HIV and Promote Sexual Health [Internet].
Vail RM, Fine SM, McGowan JP, et al.
Baltimore (MD): Johns Hopkins University; 2022 May.
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