| Component | Description |
|---|---|
| Review question | Is weekend admission associated with worse outcome than weekday admission in England (after controlling for case-mix)? |
| Objectives | To determine whether weekend admission is associated with worse outcome than weekday admission in England, after controlling for case-mix |
| Population | Adults and young people (16 years and over) with a suspected or confirmed AME |
| Presence or absence of prognostic variable | Weekend admission (or weekend attendance at ED) to include Saturday and Sunday reported together or as separate days |
| Outcome(s) |
|
| Study design | Prospective or retrospective cohort studies |
| Exclusions | Exclude studies from outside of England |
| How the information will be searched |
The databases to be searched are: Medline, Embase, the Cochrane Library Date limits for search: 10 years old (i.e., published after 2005) Language: English only |
| Key confounders | Minimum set of confounders that should be adjusted for (will vary per outcome)
|
| The review strategy | Meta-analysis where appropriate will be conducted. Studies in the following subgroup populations will be included:
In addition, if studies have pre-specified in their protocols that results for any of these subgroup populations will be analysed separately, then they will be included. The methodological quality of each study will be assessed using the Evibase checklist and GRADE. |
From: Chapter 41, Cost-effectiveness analyses
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