Table 52, Clinical evidence summary: medical outliers (adjusted for all key confounders) - Emergency and acute medical care in over 16s: service delivery and organisation

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Risk factor and outcome (population)	Number of studies	Effect (95% CI)	Imprecision	GRADE Quality
Outlier versus non-outlier for predicting serious adverse events (emergency calls) (all admitted patients)^a	1	Adjusted RR: 1.53 (1.31 to 1.77)	No serious imprecision	MODERATE

Risk factor and outcome

(population)

Number of studies

Effect (95% CI)

Imprecision

GRADE Quality

Outlier versus non-outlier for predicting serious adverse events

(emergency calls)

(all admitted patients)^a

Adjusted RR: 1.53 (1.31 to 1.77)

No serious imprecision

MODERATE

(a): Methods: multivariable analysis, including key covariates used in analysis to assess if outlier status is an independent risk factor. Key covariates included: age, case-mix, co-morbidities.

Emergency and acute medical care in over 16s: service delivery and organisation.

NICE Guideline, No. 94.

National Guideline Centre (UK).

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