Table 55Clinical evidence profile: outliers (adjusted for all key confounders)

Quality assessmentEffectQuality
No of studiesDesignRisk of biasInconsistencyIndirectnessImprecisionOther considerationsRelative (95% CI)
Serious adverse events (assessed with: emergency calls)
1Cohort studyno serious risk of biasno serious inconsistencyserious1no serious imprecisionnoneRR 1.53 (1.31 to 1.77)

⊕⊕⊕⊝

MODERATE

1

Downgraded by 1 increment if the majority of the evidence included an indirect population, or downgraded by 2 increments if the majority of the evidence included a very indirect population

From: Chapter 41, Cost-effectiveness analyses

Cover of Emergency and acute medical care in over 16s: service delivery and organisation
Emergency and acute medical care in over 16s: service delivery and organisation.
NICE Guideline, No. 94.
National Guideline Centre (UK).
Copyright © NICE 2018.

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