Table 7.

Recommended Surveillance for Individuals with WDR62 Primary Microcephaly

System/ConcernEvaluationFrequency
Neurologic
  • Monitor those w/seizures as clinically indicated.
  • Assess for new manifestations such as new-onset seizures, spasticity, contractures, & ataxia.
At each visit
Development Monitor developmental progress & educational needs.
Speech delay Speech-language pathologist: Monitor speech development.
Psychiatric/
Behavioral
  • Ancillary behavior assessment for anxiety, attention, & aggressive or self-injurious behavior
  • Refer for formal eval if concern exists.
Musculoskeletal Physical medicine, OT/PT assessment of mobility, self-help skills
Family/
Community
Assess family need for social work support (e.g., respite care, other local resources) or follow-up genetic counseling if new questions arise (e.g., family planning).

OT = occupational therapy; PT = physical therapy

From: WDR62 Primary Microcephaly

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