TABLE 13.1.

Other classes of eukaryotic glycoprotein glycosylation

ModificationExamples of proteins modifiedMotif
O-α-FucNotch, Delta, Serrate, Jagged, factor IX, urokinase, t-PA, factor XII, factor VII, CriptoEGF repeat
O-α-Fucthrombospondin 1, properdin, F-spondin, ADAMTS13, ADAMTS-like 1TSR
O-β-GlcNotch, Delta, Jagged, Crumbs-2, Eyes shut, factor VII, factor IX, protein ZEGF repeat
O-β-GlcNAcNotch, Delta, Serrate, DumpyEGF repeat
O-β-Galcollagens, surfactant protein, complement factor C1q, mannan-binding proteinscollagen repeat
O-α-Manα-dystroglycan, cadherins, plexinsmucin-like domain
C-α-ManRNase 2, thrombospondin1, properdinWXXW motif

t-PA, tissue plasminogen activator; EGF, epidermal growth factor; TSR, thrombospondin type-1 repeat.

From: Chapter 13, Other Classes of Eukaryotic Glycans

Cover of Essentials of Glycobiology
Essentials of Glycobiology [Internet]. 4th edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.
Copyright © 2022 The Consortium of Glycobiology Editors, La Jolla, California; published by Cold Spring Harbor Laboratory Press; doi:10.1101/glycobiology.4e.13. All rights reserved.

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