Table 4. [Treatment of Manifestations in Individuals with El-Hattab-Alkuraya Syndrome]. - GeneReviews®

Manifestation/Concern	Treatment	Considerations/Other
Epilepsy	Standardized treatment w/ASM by experienced neurologist	Seizures are refractory & often require at least 2 ASMs for seizure control.
Developmental delay / Intellectual disability	See Developmental Delay / Intellectual Disability Management Issues.
Spasticity / Mobility issues	Consultation w/physical medicine & rehab to help w/mobility or assistive devices (e.g., wheelchair)
Poor weight gain	Feeding therapy Nasogastric tube or gastrostomy tube are frequently needed due to feeding difficulties & poor weight gain.
Ocular manifestations	Treatment per ophthalmologist

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