Table DSummary of findings on nonpharmacologic treatment of adult treatment-resistant depression (TRD) with strength of evidence for Tier 1 (TRD) for KQ 3, comparative efficacy for particular symptom subtypes

ComparisonOutcomeNumber of SubjectsStrength of Evidence *Findings†
ECT vs. rTMSChange in depressive severity0NANo eligible studies identified. ‡

ECT = electroconvulsive therapy; NA = not applicable; rTMS = repetitive transcranial magnetic stimulation; vs. = versus

*

Strength of evidence is based on guidance provided in the AHRQ Methods Guide for Comparative Effectiveness Reviews; see text.

†

Good and fair designations relate to quality ratings for each study.

‡

At least one Tier 2 and/or Tier 3 study addressed this comparison.

From: Executive Summary

Cover of Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults
Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults [Internet].
Comparative Effectiveness Reviews, No. 33.
Gaynes BN, Lux LJ, Lloyd SW, et al.
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