Table 7Rate ratios for cardiovascular events (95% CI)*: NSAID use compared with nonuse of NSAIDs128

NSAIDNumber of StudiesRisk of Cardiovascular Events
Celecoxib111.1 (0.91 to 1.2)
Meloxicam31.2 (1.0 to 1.6)
Naproxen150.97 (0.87 to 1.1)
Diclofenac91.4 (1.2 to 1.7)
Ibuprofen161.1 (0.97 to 1.2)
Indomethacin61.3 (1.1 to 1.6)
Piroxicam41.1 (0.70 to 1.6)

CI = confidence interval; NSAID = nonsteroidal anti-inflammatory drug

From: Results

Cover of Analgesics for Osteoarthritis
Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet].
Comparative Effectiveness Reviews, No. 38.
Chou R, McDonagh MS, Nakamoto E, et al.
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