Table 10, Toxicity index scores from ARAMIS database studies - Analgesics for Osteoarthritis

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Study	Aspirin	Ibuprofen	Salsalate	Others (Range)
Fries 1991¹⁷⁷	1.19	1.94	1.28	2.17 (naproxen) to 3.99 (indomethacin)
Fries 1993¹⁷⁶	1.33	1.89	NR	1.90 (naproxen) to 2.86 (tolmetin)
Fries 1996¹⁷⁵	1.77	2.68	2.00	1.63 (sulindac) to 3.09 (ketoprofen)
Singh 1997¹⁷⁸	2.25	1.95	1.79	3.29 (naproxen) to 5.14 (meclofenamate)

: ARAMIS = Arthritis, Rheumatism, and Aging Medical Information System; NR = not reported

Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet].

Comparative Effectiveness Reviews, No. 38.

Chou R, McDonagh MS, Nakamoto E, et al.

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