[Table], Systematic Reviews - Analgesics for Osteoarthritis

Author, Year	A Priori Design Provided?	Duplicate Study Selection and Data Extraction? a. Study Selection b. Data Extraction	Comprehensive Literature Search Performed?	Status of Publication Used as an Inclusion Criteria?	List of Studies (Included and Excluded) Provided?	Characteristics of the Included Studies Provided?	Scientific Quality of Included Studies Assessed and Documented?	Scientific Quality of the Included Studies Used Appropriately in Formulating Conclusions?	Methods Used to Combine the Findings of Studies Appropriate?	Likelihood of Publication Bias Assessed?	Conflict of Interest Stated? a. Systematic Review b. Individual Studies	Quality Rating
Bjordal, 2007¹⁹⁷	Yes	Unclear; Unclear	Yes	Yes	Yes; No	Yes		Yes	Yes	No	Yes; No	Fair
Caldwell, 2006¹¹¹	Yes	Yes; Yes	Yes	Yes	Yes; No	Yes	No	No	Yes	Yes	Yes; No	Fair
Chen et al., 2008⁵⁸	Yes	Yes; Yes	Yes	Yes	Yes;Yes	Yes	Yes	Yes	Yes	No	Yes; No	Good
Hochberg, 2010¹⁹⁹	Yes	Unclear; Yes	No	Unclear	No	Yes	Yes	Yes	Yes	No	Yes; No	Fair
Juni, 2004¹²⁷	Yes	Unclear; Yes	Yes	Yes	Yes; No	Yes	Yes	Yes	Yes	Yes	Yes; Yes	Good
Kearney et al., 2006¹²¹	Yes	Unclear; Unclear	Yes	Yes	Yes; No	Yes	No	No	Yes	Yes	Yes; No	Fair
Lee, 2004¹⁷⁹	Yes	Unclear; Unclear	Yes	Yes	Yes; Yes	Yes	Yes	Yes	Yes	Yes	Yes; Yes	Good
Lee, 2010²⁰⁰	Unclear	Unclear; Unclear	Yes	No	No	Yes	Yes	Unclear	Yes	Yes	No; No	Fair
Masso Gonzalez, 2010⁹⁷	Yes	Unclear; Yes	No	No	Yes; No	Yes	No	No	Yes	No	Yes; No	Fair
Moore, 2005⁵¹	Yes	Unclear; Unclear	Yes	Yes	Yes; No	No	Yes	No	No	Yes	Yes; Yes	Fair
Niculescu, 2009¹⁷⁰	Yes	No; No	No	Yes	No	Yes	Yes	No	Unclear	No	Yes; No	Poor
Rostom, 2007⁸¹	Yes	Yes; Yes	Yes	Yes	Yes; No	Yes	Yes	Yes	Yes	No	No; No	Fair
Rostom, 2002²⁶⁴	Yes	Yes; Yes	Yes	Yes	Yes; No	No	Yes	Yes	No	Yes	Yes; No	Fair
Rubenstein, 2004¹⁶⁶	Yes	Yes; Yes	Yes	Yes	Yes; Yes	Yes	Yes	Yes	NA	No	Yes; No	Good
Solomon, 2008¹¹⁴	Yes	Unclear; Yes	Unclear	Yes	Yes; No	Yes	No	No	No	Yes	Yes; Yes	Fair
Soni, 2009¹⁶⁵	Unclear	No; Unclear	No	No	Yes; No	Yes	No	No	Yes	No	Yes; No	Fair
Towheed, 2006¹⁸⁰	Yes	Yes; Yes	Yes	Yes	Yes; Yes	Yes	Yes	Yes	Yes	Yes	Yes; Yes	Good
Towheed, 2006⁷⁰	Yes	Yes; Yes	Yes	Yes	Yes; No	Yes	Yes	Yes	Yes	No	Yes; No	Fair
Trelle 2011¹¹⁵	Yes	Yes; Yes	Yes	Yes	Yes; No	Yes	Yes	Yes	Yes	Yes	Yes; No	Good
Vlad, 2007²⁰¹	Yes	Unclear; Unclear	Yes	Yes	No	No	Yes	Yes	Yes	Yes	Yes; Yes	Good
Watson, 2006⁵⁷	Yes	Unclear; Unclear	No	Yes	Yes; No	Yes	No	No	No	No	Yes; No	Poor
Wegman, 2004¹⁸¹	Yes	Unclear; Unclear	Yes	Yes	Yes; Yes	Yes	Yes	Yes	Yes	No	Yes; No	Fair
White, 2003¹¹²	Yes	Unclear; Unclear	No	Yes	Yes; No	No	No	No	No	No	Yes; Yes	Poor
White, 2007¹¹³	Yes	Unclear; Yes	No	Yes	Yes; No	No	No	No	No	No	No; No	Poor
Zhang, 2004¹⁸²	Yes	Unclear; Yes	Yes	Yes	Yes; Yes	No	Yes	Yes	Yes	Yes	Yes; No	Good
Zhang, 2006¹⁵⁷	Unclear	Unclear; Yes	Yes	Unclear	Yes; No	Yes	No	Unclear	Yes	Yes	Yes; No	Fair

Author, Year

A Priori Design Provided?

Duplicate Study Selection and Data Extraction?
a. Study Selection
b. Data Extraction

Comprehensive Literature Search Performed?

Status of Publication Used as an Inclusion Criteria?

List of Studies (Included and Excluded) Provided?

Characteristics of the Included Studies Provided?

Scientific Quality of Included Studies Assessed and Documented?

Scientific Quality of the Included Studies Used Appropriately in Formulating Conclusions?

Methods Used to Combine the Findings of Studies Appropriate?

Likelihood of Publication Bias Assessed?

Conflict of Interest Stated?
a. Systematic Review
b. Individual Studies

Quality Rating

Bjordal, 2007¹⁹⁷

Yes

Unclear; Unclear

Yes

Yes; No

Yes

Yes; No

Fair

Caldwell, 2006¹¹¹

Yes

Yes; Yes

Yes

Yes; No

Yes

Yes; No

Fair

Chen et al., 2008⁵⁸

Yes

Yes; Yes

Yes

Yes;Yes

Yes

Yes; No

Good

Hochberg, 2010¹⁹⁹

Yes

Unclear; Yes

Unclear

Yes

Yes; No

Fair

Juni, 2004¹²⁷

Yes

Unclear; Yes

Yes

Yes; No

Yes

Yes; Yes

Good

Kearney et al., 2006¹²¹

Yes

Unclear; Unclear

Yes

Yes; No

Yes

Yes; No

Fair

Lee, 2004¹⁷⁹

Yes

Unclear; Unclear

Yes

Yes; Yes

Yes

Yes; Yes

Good

Lee, 2010²⁰⁰

Unclear

Unclear; Unclear

Yes

Unclear

Yes

No; No

Fair

Masso Gonzalez, 2010⁹⁷

Yes

Unclear; Yes

Yes; No

Yes

Yes; No

Fair

Moore, 2005⁵¹

Yes

Unclear; Unclear

Yes

Yes; No

Yes

Yes; Yes

Fair

Niculescu, 2009¹⁷⁰

Yes

No; No

Yes

Unclear

Yes; No

Poor

Rostom, 2007⁸¹

Yes

Yes; Yes

Yes

Yes; No

Yes

No; No

Fair

Rostom, 2002²⁶⁴

Yes

Yes; Yes

Yes

Yes; No

Yes

Yes; No

Fair

Rubenstein, 2004¹⁶⁶

Yes

Yes; Yes

Yes

Yes; Yes

Yes

Yes; No

Good

Solomon, 2008¹¹⁴

Yes

Unclear; Yes

Unclear

Yes

Yes; No

Yes

Yes; Yes

Fair

Soni, 2009¹⁶⁵

Unclear

No; Unclear

Yes; No

Yes

Yes; No

Fair

Towheed, 2006¹⁸⁰

Yes

Yes; Yes

Yes

Yes; Yes

Yes

Yes; Yes

Good

Towheed, 2006⁷⁰

Yes

Yes; Yes

Yes

Yes; No

Yes

Yes; No

Fair

Trelle 2011¹¹⁵

Yes

Yes; Yes

Yes

Yes; No

Yes

Yes; No

Good

Vlad, 2007²⁰¹

Yes

Unclear; Unclear

Yes

Yes; Yes

Good

Watson, 2006⁵⁷

Yes

Unclear; Unclear

Yes

Yes; No

Yes

Yes; No

Poor

Wegman, 2004¹⁸¹

Yes

Unclear; Unclear

Yes

Yes; Yes

Yes

Yes; No

Fair

White, 2003¹¹²

Yes

Unclear; Unclear

Yes

Yes; No

Yes; Yes

Poor

White, 2007¹¹³

Yes

Unclear; Yes

Yes

Yes; No

No; No

Poor

Zhang, 2004¹⁸²

Yes

Unclear; Yes

Yes

Yes; Yes

Yes

Yes; No

Good

Zhang, 2006¹⁵⁷

Unclear

Unclear; Yes

Yes

Unclear

Yes; No

Yes

Unclear

Yes

Yes; No

Fair

From: Appendix G, Quality Assessment of Trials, Systematic Reviews, and Observational Studies*

Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet].

Comparative Effectiveness Reviews, No. 38.

Chou R, McDonagh MS, Nakamoto E, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2011 Oct.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.