6OFT,1HR6,1KYO,6FO6,1Q2L,3E4A,1HR7,6XVF,6GIQ


Conserved Protein Domain Family
Peptidase_M16

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pfam00675: Peptidase_M16 
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Insulinase (Peptidase family M16)
Statistics
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PSSM-Id: 425812
Aligned: 22 rows
Threshold Bit Score: 126.266
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6OFT_B   20 YMIYPHAhPKDQVNLWLQIHTGSLQEEDNELGVAHFVEHMMFNG-TKTWPG-NKVIETFESMGLRFgrdvNAYTSYDETV 97   Escherichia coli K-12
6FO6_O   48 VIASLEN-YAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLT-TKGASS-FKITRGIEAVGGKL----SVTSTRENMA 120  cattle
P45181   45 YFVLKNTePKERVYIRLVINAGSMHEDDDQKGIAHLVEHMAFNG-SKKYPE-NQIINALEKLGMKFardiNAFTDFENTV 122  Haemophilus influen...
1Q2L_A   31 VVLLVSDpQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMG-SKKYPQaDSLAEYLKMHGGSH----NASTAPYRTA 105  Escherichia coli st...
P40851   34 LALIISDpTDTSSSCSLTVCTGSHNDPKDIAGLAHLCEHMILSAgSKKYPDpGLFHTLIAKNNGSQ----NAFTTGEQTT 109  Saccharomyces cerev...
3E4A_B   74 KVLLISDpTTDKSSAALDVHIGSLSDPPNIAGLSHFLQHMLFLG-TKKYPKeNEYSQFLSEHAGSS----NAFTSGEHTN 148  human
Q10040   37 RVLLVSDsKTRVSAVALDVKVGHLMDPWELPGLAHFCEHMLFLG-TAKYPSeREYFKYLAANNGDS----NAYTDTDHTN 111  Caenorhabditis elegans
P22817   47 KVLLISDpNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLG-TEKYPHeNGYTTYLSQSGGSS----NAATYPLMTK 121  fruit fly
P47245  210 RVEARKKtTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMG-SLKYPDeNGFDAFLKKHGGSD----NASTDCERTV 284  Norway rat
Q04805   12 RIVLENNpTVRSVAIGVWIGTGSRHETPEINGISHFLEHMFFKG-TSTKSA-REIAESFDRIGGQV----NAFTSKEYTC 85   Bacillus subtilis s...
6OFT_B   98 YQVSLPTTQkq---nLQQVMAIFSEWSNAATFEKLEVDAERGvITEEWRAHQDAKWrtSQARRPFLLANTRNLDREPIGL 174  Escherichia coli K-12
6FO6_O  121 YTVECLRDD------VDILMEFLLNVTTAPEFRRWEVAA--L-QPQLRIDKAVALQnpQAHVIENLHAAAYR-NALANSL 190  cattle
P45181  123 YTLNLDSNNqq---kLELAFDVINEWMNNITFLPKDVDG--------ERGVVQEEW-------RRRLSPMLRIGNKKSAI 184  Haemophilus influen...
1Q2L_A  106 FYLEVENDA------LPGAVDRLADAIAEPLLDKKYAER--------ERNAVNAEL------TMARTRDGMRMAQVSAET 165  Escherichia coli st...
P40851  110 FYFELPNTQnngeftFESILDVFASFFKEPLFNPLLISK--------EIYAIQSEH------EGNISSTTKIFYHAARIL 175  Saccharomyces cerev...
3E4A_B  149 YYFDVSHEH------LEGALDRFAQFFLSPLFDESAKDR--------EVNAVDSEH------EKNVMNDAWRLFQLEKAT 208  human
Q10040  112 YSFEVRSEK------LYGALDRFAQFFLDPQFTESATER--------EVCAVNCEY------LDKVNEDFWRCLQVERSL 171  Caenorhabditis elegans
P22817  122 YHFHVAPDK------LDGALDRFAQFFIAPLFTPSATER--------EINAVNSEH------EKNLPSDLWRIKQVNRHL 181  fruit fly
P47245  285 FQFDVQRKY------FKEALDRWAQFFIHPLMIRDAIDR--------EVEAVDSEY------QLARPSDANRKEMLFGSL 344  Norway rat
Q04805   86 YYAKVLDEH------ANYALDVLADMFFHSTFDENELKKEKN-VVYEEIKMYEDAP--DDIVHDLLSKATYGNHSLGYPI 156  Bacillus subtilis s...
6OFT_B  175 MDTV 178  Escherichia coli K-12
6FO6_O  191 YCPD 194  cattle
P45181  185 EMAG 188  Haemophilus influenzae Rd KW20
1Q2L_A  166 INPA 169  Escherichia coli str. K-12 substr. W3110
P40851  176 ANPD 179  Saccharomyces cerevisiae S288C
3E4A_B  209 GNPK 212  human
Q10040  172 SKPG 175  Caenorhabditis elegans
P22817  182 AKPD 185  fruit fly
P47245  345 ARPG 348  Norway rat
Q04805  157 LGTE 160  Bacillus subtilis subsp. subtilis str. 168
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