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Items: 1 to 20 of 340

1.

On the genetic constitution of the Marquesas

(Submitter supplied) We combined new data with previously published data (PMID: 24297229, 21940856, 33753914, 27302840, 25877615, 18292342, 26811443, 30846778 and 29379068) to examine the genetic history of three groups from Marquesan Islands
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platforms:
GPL31092 GPL22678
32 Samples
Download data: TXT
Series
Accession:
GSE190958
ID:
200190958
2.

The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

(Submitter supplied) We combined new data with previously published data (PMID: 25877615, 26811443, 29379068, 18292342, 24297229, 27302840, 24395773 and 30846778) to compare phylogenetic relationships of the Ami and Yami aborigenes of Taiwan to groups from mainland Southeast Asia, island Southeast Asia and Oceania.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; SNP genotyping by SNP array
Platform:
GPL22678
43 Samples
Download data: TXT
Series
Accession:
GSE152194
ID:
200152194
3.

Cell-type specific multi-QTL analyses of cultured human primary melanocytes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Methylation profiling by array; SNP genotyping by SNP array
Platforms:
GPL22678 GPL13534
230 Samples
Download data: IDAT
Series
Accession:
GSE166102
ID:
200166102
4.

Aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL8888 GPL22678 GPL13135
347 Samples
Download data
Series
Accession:
GSE152200
ID:
200152200
5.

Trunk events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by SNP array
4 related Platforms
315 Samples
Download data
Series
Accession:
GSE98620
ID:
200098620
6.

Trunk events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma [early CNV]

(Submitter supplied) Introduction: According to the clonal model of tumor evolution, trunk alterations arise at early stages and are ubiquitous. Through the characterization of early stages of hepatocarcinogenesis, we aimed to identify trunk alterations in HCC and study their intra- and inter-tumor distribution in more advanced lesions. Methods: 151 samples representing the multi-step process of hepatocarcinogenesis were analyzed by targeted-sequencing and SNP array. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array
Platform:
GPL22678
82 Samples
Download data: TXT
Series
Accession:
GSE98619
ID:
200098619
7.

The genetic legacy of continental scale admixture in Indian Austroasiatic speakers

(Submitter supplied) We combined new data with previously published data to characterize admixture patterns of Austroasiatic speaking populations of India in the context of their geographic neighbours across Eurasia
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL22678 GPL8888
39 Samples
Download data: TXT
Series
Accession:
GSE126882
ID:
200126882
8.

Expression quantitative trait loci of primary melanocytes facilitate identification of melanoma susceptibility genes

(Submitter supplied) eQTL is a powerful method to detect genotype-expression correlation. To be able to identify the genes whose expression levels are correlated with germline genetic variants including the ones associated with melanoma, eQTL analysis was performed in 106 primary melanocyte cultrures
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platform:
GPL22678
124 Samples
Download data: IDAT, TXT
Series
Accession:
GSE101771
ID:
200101771
9.

Germline variant in SLCO2B1 and response to abiraterone acetate plus prednisone (AA) in new onset metastatic castration-resistant prostate cancer (mCRPC)

(Submitter supplied) There are many treatment options available for men with metastatic castration-resistant prostate cancer (mCRPC). Yet, biomarkers predictive of differential response to treatment are currently available. A recent translational study suggested that SLCO2B1 genotype could predict response to abiraterone acetate (AA) for men with advanced prostate cancer. Here, we investigate whether germline variants in SLCO2B1 are predictive of response to first-line AA in men with new mCRPC. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array
Platforms:
GPL21168 GPL25924 GPL22678
79 Samples
Download data: TXT
Series
Accession:
GSE123695
ID:
200123695
10.

The genetic ancestry of modern Indus Valley populations from Northwest India

(Submitter supplied) We genotyped 45 new samples from 4 populations of Northwest India and combined it with previously published data to characterize the population structure of modern Northwest Indian populations in the context of their geographic neighbors across South Asia and West Eurasia.
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platforms:
GPL22678 GPL21168
45 Samples
Download data: TXT
Series
Accession:
GSE119653
ID:
200119653
11.

Establishment and characterization of prostate cancer organoids

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; Expression profiling by high throughput sequencing
Platforms:
GPL21290 GPL22678 GPL16791
20 Samples
Download data: TXT
Series
Accession:
GSE113743
ID:
200113743
12.

Establishment and characterization of prostate cancer organoids [array]

(Submitter supplied) Prostate cancer translational research has been hampered by the lack of comprehensive and tractable models that represent the genomic landscape of clinical disease. Metastatic castrate-resistant prostate cancer (mCRPC) patient derived xenografts (PDXs) recapitulate the genetic and phenotypic diversity of the disease. We sought to establish a representative, preclinical platform of PDX-derived organoids that is experimentally facile for high throughput and mechanistic analysis.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array
Platform:
GPL22678
12 Samples
Download data: SEG
Series
Accession:
GSE113709
ID:
200113709
13.

SNP Genotype and Gene Expression data from induced Pluripotent Stem cells from Parkinson's Disease patients harboring mutations in the GBA1 gene, and from healthy control donors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; SNP genotyping by SNP array; Genome variation profiling by SNP array
Platforms:
GPL13829 GPL10558 GPL22678
18 Samples
Download data
Series
Accession:
GSE99473
ID:
200099473
14.

SNP genotype data from induced Pluripotent Stem cells from Parkinson's Disease patients harboring mutations in the GBA1 gene, and from healthy control donors

(Submitter supplied) We have generated human induced Pluripotent Stem cells (hiPSc) using Retroviral and Sendai virus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess chromosomal stability (alongside the fibroblast lines from which they were derived), and validation of the pluripotency of the hiPSc lines is provided by Pluritest assessment of transcriptome datasets, prior to differentiation and downstream assays. more...
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array; Genome variation profiling by SNP array
Platforms:
GPL13829 GPL22678
13 Samples
Download data: TXT
Series
Accession:
GSE99471
ID:
200099471
15.

Human induced pluripotent stem cell-derived macrophages share ontogeny with MYB-independent tissue-resident macrophages

(Submitter supplied) Tissue-resident macrophages such as microglia, Kupffer and Langerhans cells derive from Myb-independent yolk sac (YS) progenitors generated before the emergence of hematopoietic stem cells (HSCs). Myb-independent YS-derived resident macrophages self-renew locally, independently of circulating monocytes and HSCs. In contrast, adult blood monocytes as well as infiltrating, gut and dermal macrophages derive from Myb-dependent HSCs. more...
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platform:
GPL22678
7 Samples
Download data: TXT
Series
Accession:
GSE93285
ID:
200093285
16.

Gene expression data from induced Pluripotent Stem cells from Parkinson's Disease patients harbouring amplification of, or mutations in the SNCA gene, and from healthy control donors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; SNP genotyping by SNP array
4 related Platforms
32 Samples
Download data
Series
Accession:
GSE89886
ID:
200089886
17.

Gene expression data from induced Pluripotent Stem cells from Parkinson's Disease patients harbouring amplification of, or mutations in the SNCA gene, and from healthy control donors [genotype]

(Submitter supplied) We have generated human induced Pluripotent Stem cells (hiPSc) using Sendai virus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess chromosomal stability (alongside the fibroblast lines from which they derived), and validation of the pluripotency of the hiPSc lines is provided by Pluritest assessment of transcriptome datasets, prior to differentiation and downstream assays. more...
Organism:
Homo sapiens
Type:
SNP genotyping by SNP array
Platforms:
GPL13829 GPL21168 GPL22678
19 Samples
Download data: TXT
Series
Accession:
GSE89878
ID:
200089878
18.

HumanOmniExpress-24 v1.1 BeadChip [SNP_ID version]

(Submitter supplied) See manufacturer's website
Organism:
Homo sapiens
17 Series
322 Samples
Download data
Platform
Accession:
GPL22678
ID:
100022678
19.

Laos27

Organism:
Homo sapiens
Source name:
blood
Platform:
GPL22678
Series:
GSE190958
Download data
Sample
Accession:
GSM5736360
ID:
305736360
20.

Laos19

Organism:
Homo sapiens
Source name:
blood
Platform:
GPL22678
Series:
GSE190958
Download data
Sample
Accession:
GSM5736359
ID:
305736359
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