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1.

Gene Expression during Panobinostat Dosing

(Submitter supplied) A clinical study evaluating the dosing of an oral HDACi panobinostat in patient infected with HIV-1. Dosing was 20 mg orally, 3 times weekly, every other week for a total of 8 weeks. Gene expression was evaluated in whole PBMCs at baseline (Visit 2), after 3 doses (Visit 4), 4 weeks after dosing (Visit 12) and 6 months after dosing (Visit 13) using the Affymetrix HTA 2.0 gene expression chip
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17586
60 Samples
Download data: CEL, CHP
Series
Accession:
GSE109792
ID:
200109792
2.

[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]

(Submitter supplied) #%create_date=Wed Jan 22 15:39:59 2014 PST #%chip_type=HTA-2_0 #%lib_set_name=HTA-2_0 #%lib_set_version=r1 #%genome-species=Homo sapiens #%genome-version=hg19 #%genome-version-ucsc=hg19 #%genome-version-ncbi=GRCh37 #%genome-version-create_date=2009-02-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Homo sapiens #%genome-lifted_from-version-ucsc=hg19 #%genome-lifted_from-version-ncbi=GRCh37 #%netaffx-annotation-date=2013-10-15 #%netaffx-annotation-netaffx-build=34 Protocol: See manufacturers website
Organism:
Homo sapiens
631 Series
11 Related Platforms
19203 Samples
Download data
Platform
Accession:
GPL17586
ID:
100017586
3.

PBMC at Visit 13, ID 19

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 6 months after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967456
ID:
302967456
4.

PBMC at Visit 12, ID 19

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 4 weeks after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967455
ID:
302967455
5.

PBMC at Visit 4, ID 19

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 after three doses (20 mg oral) panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967454
ID:
302967454
6.

PBMC at baseline, ID 19

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 before dosing with panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967453
ID:
302967453
7.

PBMC at Visit 13, ID 18

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 6 months after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967452
ID:
302967452
8.

PBMC at Visit 12, ID 18

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 4 weeks after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967451
ID:
302967451
9.

PBMC at Visit 4, ID 18

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 after three doses (20 mg oral) panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967450
ID:
302967450
10.

PBMC at baseline, ID 18

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 before dosing with panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967449
ID:
302967449
11.

PBMC at Visit 13, ID 17

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 6 months after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967448
ID:
302967448
12.

PBMC at Visit 12, ID 17

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 4 weeks after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967447
ID:
302967447
13.

PBMC at Visit 4, ID 17

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 after three doses (20 mg oral) panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967446
ID:
302967446
14.

PBMC at baseline, ID 17

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 before dosing with panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967445
ID:
302967445
15.

PBMC at Visit 13, ID 15

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 6 months after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967444
ID:
302967444
16.

PBMC at Visit 12, ID 15

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 4 weeks after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967443
ID:
302967443
17.

PBMC at Visit 4, ID 15

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 after three doses (20 mg oral) panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967442
ID:
302967442
18.

PBMC at baseline, ID 15

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 before dosing with panobinostat
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967441
ID:
302967441
19.

PBMC at Visit 13, ID 14

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 6 months after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967440
ID:
302967440
20.

PBMC at Visit 12, ID 14

Organism:
Homo sapiens
Source name:
PBMCs from humans infected with HIV-1 4 weeks after total of 8 weeks of panobinostat dosing
Platform:
GPL17586
Series:
GSE109792
Download data: CEL, CHP
Sample
Accession:
GSM2967439
ID:
302967439
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