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Items: 20

1.

Sequencing-Guided Design of Genetically Encoded Small RNAs Targeting CAG Repeats for Selective Inhibition of Mutant Huntingtin [II]

(Submitter supplied) Huntington’s disease (HD) is an incurable neurodegenerative disorder caused by genetic expansion of a CAG repeat sequence in one allele of the huntingtin (HTT) gene. Reducing expression of the mutant HTT (mutHTT) protein has remained a clear therapeutic goal but reduction of wild-type HTT (wtHTT) is undesirable as it compromises gene function and potential therapeutic efficacy. One promising allele- selective approach involves targeting the CAG repeat expansion with steric binding small RNAs bearing central mismatches. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26167
18 Samples
Download data: CSV, TXT
Series
Accession:
GSE264218
ID:
200264218

PubMed Full text in PMC Similar studies

2.

PromethION (Homo sapiens)

Organism:
Homo sapiens
80 Series
402 Samples
Download data
Platform
Accession:
GPL26167
ID:
100026167

3.

Parasrampuria_mRNA_Seq_shHD-33full_UAC_3

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214591
ID:
308214591

SRA Run Selector

4.

Parasrampuria_mRNA_Seq_shHD-33full_UAC_2

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214590
ID:
308214590

SRA Run Selector

5.

Parasrampuria_mRNA_Seq_shHD-33full_UAC_1

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214589
ID:
308214589

SRA Run Selector

6.

Parasrampuria_mRNA_Seq_shHD-33full_nb_3

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214588
ID:
308214588

SRA Run Selector

7.

Parasrampuria_mRNA_Seq_shHD-33full_nb_2

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214587
ID:
308214587

SRA Run Selector

8.

Parasrampuria_mRNA_Seq_shHD-33full_nb_1

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214586
ID:
308214586

SRA Run Selector

9.

Parasrampuria_mRNA_Seq_shHD-33full-mimic_3

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214585
ID:
308214585

SRA Run Selector

10.

Parasrampuria_mRNA_Seq_shHD-33full-mimic_2

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214584
ID:
308214584

SRA Run Selector

11.

Parasrampuria_mRNA_Seq_shHD-33full-mimic_1

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214583
ID:
308214583

SRA Run Selector

12.

Parasrampuria_mRNA_Seq_shHD2.4_3

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214582
ID:
308214582

SRA Run Selector

13.

Parasrampuria_mRNA_Seq_shHD2.4_2

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214581
ID:
308214581

SRA Run Selector

14.

Parasrampuria_mRNA_Seq_shHD2.4_1

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214580
ID:
308214580

SRA Run Selector

15.

Parasrampuria_mRNA_Seq_shMCHR_3

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214579
ID:
308214579

SRA Run Selector

16.

Parasrampuria_mRNA_Seq_shMCHR_2

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214578
ID:
308214578

SRA Run Selector

17.

Parasrampuria_mRNA_Seq_shMCHR_1

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214577
ID:
308214577

SRA Run Selector

18.

Parasrampuria_mRNA_Seq_mock_3

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214576
ID:
308214576

SRA Run Selector

19.

Parasrampuria_mRNA_Seq_mock_2

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214575
ID:
308214575

SRA Run Selector

20.

Parasrampuria_mRNA_Seq_mock_1

Organism:
Homo sapiens
Source name:
Coriell Institute HD fibroblasts (GM04281)
Platform:
GPL26167
Series:
GSE264218 GSE264444
Download data
Sample
Accession:
GSM8214574
ID:
308214574

SRA Run Selector

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