GSM1291450[Accession] - GEO DataSets

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Items: 3

Select item 2000533481.

Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

(Submitter supplied) The DNA sequence preferences of the vast majority of eukaryotic transcription factors (TFs) are unknown. Using an approach designed to broadly sample both DNA-binding domain types and eukaryotic clades, we have determined DNA-binding motifs for 1,033 TFs from 131 diverse eukaryotes, encompassing 54 domain types. Closely related orthologs and paralogs typically have very similar sequence preferences; this property allows inference of motifs for roughly one third of the 166,851 known or predicted eukaryotic TFs. more...

Organism:: synthetic construct

Type:: Other

Platform:: GPL11260
2064 Samples

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Accession:: GSE53348

ID:: 200053348

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000112602.

Agilent custom ME and HK design array [8mer]

(Submitter supplied) 8mer sequence depicted below is not the sequence represented on the array, but the targeted sequence. Please see the two array design files attached below for array probe sequences. Protocol: This protein binding microarray (PBM) involved binding GST-tagged proteins to custom-designed, double-stranded 44K Agilent microarrays in order to determine their sequence preferences. The method is described in Berger et al., Nature Biotechnology 2006.