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Items: 4

1.

Genome-wide chromatin profiles of PBRM1 [ChIP-Seq]

(Submitter supplied) PBRM1 encodes an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and the inactivation of PBRM1 is the second most frequent mutational event in kidney cancer. However, the impact of PBRM1 loss on chromatin remodeling, especially pertaining to kidney tumorigenesis, has not been well examined. Here we show that in VHL-deficient renal tumors, PBRM1 deficiency results in aberrant PBAF complexes that localize to de novo genomic loci and activate the pro-tumorigenic NF-?B pathway. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL20301 GPL16791
77 Samples
Download data: BED
Series
Accession:
GSE152681
ID:
200152681
2.

Genome-wide chromatin profiles of PBRM1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
5 related Platforms
170 Samples
Download data: BED, NARROWPEAK
Series
Accession:
GSE152735
ID:
200152735
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

Input_NCC010_PBRM1_ChIPSeq

Organism:
Homo sapiens
Source name:
Cancer cell line
Platform:
GPL16791
Series:
GSE152681 GSE152735
Download data
Sample
Accession:
GSM4623505
ID:
304623505
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Supplemental Content

db=gds|term=GSM4623505[Accession]|query=1|qty=2|blobid=MCID_66c835b8c8112916c0c8ecf5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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