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Items: 4

1.

Genome-wide chromatin profiles of PBRM1 [RNA-Seq]

(Submitter supplied) PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler. The inactivation of PBRM1 is the second most frequent mutational event in kidney tumorigenesis. Here we show that in VHL-deficient ccRCC tumors, PBRM1 loss results in an altered PBAF complex that retains the association between SMARCA4 and ARID2 but disengages BRD7 from SMARCA4. The PBRM1-deficient PBAF complexes redistribute from promoter proxy regions to distal enhancer regions. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20795 GPL24676 GPL11154
41 Samples
Download data: TXT
Series
Accession:
GSE152734
ID:
200152734
2.

Genome-wide chromatin profiles of PBRM1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
5 related Platforms
170 Samples
Download data: BED, NARROWPEAK
Series
Accession:
GSE152735
ID:
200152735
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

NCC432_PBRM1_Rep2

Organism:
Homo sapiens
Source name:
Cancer cell line
Platform:
GPL11154
Series:
GSE152734 GSE152735
Download data
Sample
Accession:
GSM4625405
ID:
304625405
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Supplemental Content

db=gds|term=GSM4625405[Accession]|query=1|qty=2|blobid=MCID_66c83dd4ba59ee397a844ab6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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