GSM484819[Accession] - GEO DataSets

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Items: 4

Select item 2000195101.

Transcriptional response of normal human lung WI-38 fibroblasts to benzo[a]pyrene diol epoxide: a dose-response study

(Submitter supplied) Cellular responses to carcinogens are typically studied in transformed cell lines, which do not reflect the physiological status of normal tissues. To address this question, we have characterized the transcriptional program and cellular responses of normal human lung WI-38 fibroblasts upon exposure to the ultimate carcinogen benzo[a]pyrene diol epoxide (BPDE). Exposure to BPDE induces a strong inflammatory response in WI-38 primary fibroblasts. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3706
Platform:: GPL570
14 Samples

Download data: CEL

Series

Accession:: GSE19510

ID:: 200019510

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 37062.

Benzo[a]pyrene diol epoxide effect on lung WI-38 fibroblasts: dose-response

Analysis of normal lung WI-38 fibroblasts exposed to various concentrations of the carcinogen benzo[a]pyrene diol epoxide (BPDE). BPDE is a metabolite of benzo[a]pyrene, a component of cigarette smoke. Results provide insight into the molecular response of normal lung fibroblasts to BPDE.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 4 dose sets

Platform:: GPL570
Series:: GSE19510
14 Samples

Download data: CEL

DataSet

Accession:: GDS3706

ID:: 3706

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...