GSM5188051[Accession] - GEO DataSets

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Items: 4

Select item 2001692351.

Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify differences in DNA methylation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Rattus norvegicus; Mus musculus; Homo sapiens

Type:: Methylation profiling by genome tiling array; Methylation profiling by high throughput sequencing

Platforms:: GPL17021 GPL28271
205 Samples

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Accession:: GSE169235

ID:: 200169235

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Select item 2001692342.

Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify differences in DNA methylation [RRBS]

(Submitter supplied) Background The combination of sodium bisulfite treatment with highly-parallel sequencing is a common method for quantifying DNA methylation across the genome. The power to detect between-group differences in DNA methylation using bisulfite-sequencing approaches is influenced by both experimental (e.g. read depth, missing data and sample size) and biological (e.g. mean level of DNA methylation and difference between groups) parameters. more...