GSM6067372[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2001526811.

Genome-wide chromatin profiles of PBRM1 [ChIP-Seq]

(Submitter supplied) PBRM1 encodes an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and the inactivation of PBRM1 is the second most frequent mutational event in kidney cancer. However, the impact of PBRM1 loss on chromatin remodeling, especially pertaining to kidney tumorigenesis, has not been well examined. Here we show that in VHL-deficient renal tumors, PBRM1 deficiency results in aberrant PBAF complexes that localize to de novo genomic loci and activate the pro-tumorigenic NF-?B pathway. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL20301 GPL16791
77 Samples

Download data: BED

Series

Accession:: GSE152681

ID:: 200152681

PubMed Similar studies SRA Run Selector

Select item 2001527352.

Genome-wide chromatin profiles of PBRM1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

5 related Platforms
170 Samples

Download data: BED, NARROWPEAK

Series

Accession:: GSE152735

ID:: 200152735

PubMed Similar studies

Select item 1000203013.

Illumina HiSeq 4000 (Homo sapiens)

Organism:: Homo sapiens

8479 Series
194318 Samples

Platform

Accession:: GPL20301

ID:: 100020301

Select item 3060673724.

Input_PE_786O_PBRM1WT_Rep3

Organism:: Homo sapiens

Source name:: Cancer cell line

Platform:: GPL20301
Series:: GSE152681 GSE152735

Sample

Accession:: GSM6067372

ID:: 306067372

SRA Run Selector

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