GSM632133[Accession] - GEO DataSets

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Items: 3

Select item 2000257231.

Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays

(Submitter supplied) C2H2 zinc fingers (C2H2-ZFs) are the most prevalent type of vertebrate DNA-binding domain, and typically appear in tandem arrays (ZFAs), with sequential C2H2-ZFs each contacting 3 (or more) sequential bases. C2H2-ZFs can be assembled in a modular fashion, providing one explanation for their remarkable evolutionary success. Given a set of modules with defined 3-base specificities, modular assembly also presents a way to construct artificial proteins with specific DNA-binding preferences. more...

Organism:: synthetic construct

Type:: Other

Platforms:: GPL11260 GPL11261
80 Samples

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Accession:: GSE25723

ID:: 200025723

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000112602.

Agilent custom ME and HK design array [8mer]

(Submitter supplied) 8mer sequence depicted below is not the sequence represented on the array, but the targeted sequence. Please see the two array design files attached below for array probe sequences. Protocol: This protein binding microarray (PBM) involved binding GST-tagged proteins to custom-designed, double-stranded 44K Agilent microarrays in order to determine their sequence preferences. The method is described in Berger et al., Nature Biotechnology 2006.