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Items: 2

1.

Laser capture microdissection of endothelial and neuronal cells from human dorsolateral prefrontal cortex

(Submitter supplied) We used laser capture microdissection to isolate both microvascular endothelial cells and neurons from post mortem brain tissue from patients with schizophrenia and bipolar disorder and healthy controls. RNA was isolated from these cell populations, amplified, and analysed using Affymetrix HG133plus2.0 GeneChips. In the first instance, we used the dataset to compare the neuronal and endothelial data, in order to demonstrate that the predicted differences between cell types could be detected using this methodology. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3502
Platform:
GPL570
32 Samples
Download data: CEL
Series
Accession:
GSE12679
ID:
200012679
2.
Full record GDS3502

Schizophrenia: endothelial and neuronal cells from postmortem dorsolateral prefrontal cortex tissue

Analysis of LCM-captured microvascular endothelial cells and neurons from post mortem brain tissue from schizophrenia patients, bipolar disorder patients, and healthy controls. Results provide insight into molecular mechanisms underlying the pathophysiology of schizophrenia.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 18 age, 2 cell type, 3 disease state, 2 gender sets
Platform:
GPL570
Series:
GSE12679
32 Samples
Download data: CEL

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