Similar studies for GEO DataSets (Select 200001659) - GEO DataSets

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Items: 16

Select item 2000016591.

Time series of diabetes and exercise training induced expression changes in skeletal muscle of mice

(Submitter supplied) Experiment protocol: Experiment was performed on 10 to 15 weeks old male NMRI mice (Harlan, Holland) housed in standard conditions (temperature 22°C, humidity 60 ± 10 %, artificial light from 8.00 am to 8.00 pm, normally 5 animals per cage). Animals had free access to tap water and food pellets (R36, Labfor, Stockholm, Sweden). Animals were randomly divided into healthy and diabetic groups. The diabetic group received a single peritoneal injection of streptozotocin (STZ, Sigma-Aldrich, France, 180 mg/kg) dissolved in sodium citrate buffer solution (0.1 mol/l, pH 4.5) to induce experimental diabetes similar to type 1. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1541
Platform:: GPL81
12 Samples

Download data: CEL, EXP

Series

Accession:: GSE1659

ID:: 200001659

Select item 2000046162.

Time series of diabetes and exercise training induced expression changes in cardiac muscle of mice

(Submitter supplied) We investigated the effects of diabetes, physical training, and their combination on the gene expression of cardiac muscle. Mice were divided to control (C), training (T), streptozotocin-induced diabetic (D), and diabetic training (DT) groups. Training groups performed 1, 3, or 5 weeks of endurance training on a motor-driven treadmill. Muscle samples from T and DT groups together with respective controls were collected 24 hours after the last training session. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2335
Platform:: GPL81
12 Samples

Download data: CEL, EXP

Series

Accession:: GSE4616

ID:: 200004616

Select item 23353.

Exercise effect on the diabetic cardiac muscle: time course

Analysis of experimental type 1 diabetic cardiac muscles of NMRI males subjected to endurance training for up to 5 weeks. Diabetes induced by a single peritoneal injection of streptozotocin.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 disease state, 2 protocol, 3 time sets

Platform:: GPL81
Series:: GSE4616
12 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS2335

ID:: 2335

Select item 15414.

Exercise effect on diabetic skeletal muscle: time course

Analysis of experimental type 1 diabetic skeletal muscle subjected to endurance training. Diabetic muscle atrophy is accompanied by changes in the extracellular matrix (ECM). Results suggest the diabetes-induced decrease in gene expression of ECM proteins is partially attenuated by training.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 disease state, 2 protocol, 3 time sets

Platform:: GPL81
Series:: GSE1659
12 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1541

ID:: 1541

Select item 2000033135.

Impaired revascularization in a mouse model of diabetes associated with dysregulation of angiogenic-regulatory network.

(Submitter supplied) Diabetes is a risk factor for the development of cardiovascular diseases that are associated with impaired angiogenesis or increased endothelial cell apoptosis. Here is it shown that angiogenic repair of ischemic hind limbs was impaired in Lepr db/db mice, a leptin receptor deficient model of diabetes, compared to wild-type C57BL/6 (WT) mice as evaluated by laser Doppler flow and capillary density analyses. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
24 Samples

Download data

Series

Accession:: GSE3313

ID:: 200003313

Select item 2000068806.

Heart in Diabetes

(Submitter supplied) 8 week old rats injected with streptozotocin or buffer alone at age of 8 weeks, heart obtained at 12 weeks (thus animals were diabetic for 4 weeks). Left vent of heart. Keywords: Disease state analysis (diabetes)

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3153
Platform:: GPL341
6 Samples

Download data: CEL

Series

Accession:: GSE6880

ID:: 200006880

Select item 31537.

Diabetes model: heart

Analysis of heart left ventricles of diabetic animals. Diabetes induced by streptozotocin treatment. Results provide insight into the molecular mechanisms underlying diabetes-induced cardiac dysfunction.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL341
Series:: GSE6880
6 Samples

Download data: CEL

DataSet

Accession:: GDS3153

ID:: 3153

Select item 2000030688.

normal and diabetic rat muscle treated and untreated with vanadyl sulfate

(Submitter supplied) RNA was obtained from rear leg muscle of normal and diabetic rats in the presence and absence of oral treatment with vandyl sulfate. Diabetes was induced with streptozotocin and expression profiles were determined using Affymetrix Rat Genechip U34A. The effect of treatment and disease on gene expression was examined. Keywords: vanadium treatment

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS1913
Platform:: GPL85
20 Samples

Download data

Series

Accession:: GSE3068

ID:: 200003068

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 19139.

Streptozotocin-induced diabetic muscle response to vanadyl sulfate

Expression profiling of rear leg muscles of diabetic Wistars treated with vanadyl sulfate. Diabetes induced with streptozotocin (STZ). Studies show that vanadyl sulfate relieves diabetic hyperglycemia.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 2 agent, 2 disease state sets

Platform:: GPL85
Series:: GSE3068
20 Samples

Download data

DataSet

Accession:: GDS1913

ID:: 1913

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20005892910.

Exercise promotes growth and vascularization of fast skeletal muscle by activating myogenic and angiogenic transcriptional programs in adult zebrafish

(Submitter supplied) The adult skeletal muscle is a plastic tissue with a remarkable ability to adapt to different levels of activity by altering its excitability, its contractile and metabolic phenotype and its mass. Knowledge on the mechanisms responsible for muscle mass comes primarily from models of muscle inactivity or denervation or from genetic models of muscle diseases. Given that the underlying exercise-induced transcriptional mechanisms regulating muscle mass are not fully understood, here we investigated the cellular and molecular adaptive mechanisms taking place in fast skeletal muscle of adult zebrafish in response to swimming. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL13390
16 Samples

Download data: TXT

Series

Accession:: GSE58929

ID:: 200058929

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001362311.

Hypoxic endurance exercise in an untrained or six weeks trained state

(Submitter supplied) Time course of mRNA after 30 minutes of endurance exercise at simulated altitude of 4000 m in an untrained or six weeks trained state of six subjects.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1935
44 Samples

Download data

Series

Accession:: GSE13623

ID:: 200013623

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000247912.

Endurance exercise in an untrained or six weeks trained state

(Submitter supplied) Time course of mRNA after 30 minutes of endurance exercise in an untrained (1) or six weeks trained state (2) of six subjects (Hoxxx) Ho980: (1) GSM47111, GSM47112, GSM47113, GSM47114, (2) GSM47115, GSM47116, GSM47125, GSM47126 Ho983: (1) GSM47129, GSM47131, GSM47135, GSM47136, (2) GSM47139, GSM47142, GSM47144, GSM47145 Ho985: (1) GSM47146, GSM47147, GSM47148, GSM47149, (2) GSM47155, GSM47159, GSM47160, GSM47161 Ho995: (1) GSM47162, GSM47163, GSM47164, GSM47165, (2) GSM47166, GSM47167, GSM47168, GSM47169 Ho997: (1) GSM47170, GSM47171, GSM47172, GSM47173, (2) GSM47174, GSM47175, GSM47176, GSM47177 Ho999: (1) GSM47178, GSM47179, GSM47180, GSM47181, (2) GSM47182, GSM47185, GSM47195, GSM47196 Keywords: time-course

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1935
48 Samples

Download data

Series

Accession:: GSE2479

ID:: 200002479

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000511013.

48h Immobilization in human

(Submitter supplied) Our results suggest that 48h of immobilization increases expression of mRNA for components of the UPP and MT function while decreasing mRNA and protein for components involved in ECM integrity. We hypothesized that 48h of immobilization would increase gene expression and respective protein products for components of the ubiquitin proteasome pathway (UPP). Keywords: stimulus or stress design

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2083
Platform:: GPL570
10 Samples

Download data: CEL

Series

Accession:: GSE5110

ID:: 200005110

Select item 208314.

Limb immobilization effect on skeletal muscle

Analysis of vastus lateralis muscle after knee immobilization for 48 hours. Limbs immobilized due to injury or illness experience significant muscle atrophy within 1 or 2 weeks. Results provide insight into the mechanisms regulating the rapid protein degradation in immobilized skeletal muscles.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 5 individual, 2 stress sets

Platform:: GPL570
Series:: GSE5110
10 Samples

Download data: CEL

DataSet

Accession:: GDS2083

ID:: 2083

Select item 20005359815.

Effects of mixed exercise training on gene expression in human skeletal muscle

(Submitter supplied) Background: Exercise has a positive effect on overall health. This study was performed to get an overview of the effects of mixed exercise training on skeletal muscl

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL11532
36 Samples

Download data: CEL

Series

Accession:: GSE53598

ID:: 200053598

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20004350016.

Global transcriptome analysis on Ankrd2 deficient or overexpressing differentiating primary myoblasts

(Submitter supplied) To provide insights into the role of Ankrd2 in the pathways controlling myogenic differentiation, the gene networks that are disturbed in Ankrd2 knockout or overexpressing primary cells were explored during differentiation. Ankrd2 plays an important role in myogenic differentiation by modulating the activity of its interacting partners (i.e p53). Since Ankrd2 binds to numerous transcription factors many signaling pathways remained to be explored to determine the functional significance of crosstalk between Ankrd2 and the activation of transcriptional programmes that regulate muscle remodeling. more...